Treatment of immune-mediated temporal lobe epilepsy with GAD antibodies

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چکیده

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Treatment of immune-mediated temporal lobe epilepsy with GAD antibodies

PURPOSE Temporal lobe epilepsy with antibodies (abs) against the glutamic acid decarboxylase 65 isoform (GAD-TLE) is known as an immune-mediated neurological syndrome. Here we evaluate the therapy response to various immunotherapies and epilepsy surgery in this syndrome. METHOD All patients with GAD-TLE and follow-up data and stored serum and CSF samples, identified and treated at the Bonn ce...

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Comparison of temporal lobe epilepsy with hippocampal sclerosis and temporal lobe epilepsies due to other etiologies

  Background: This study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) with those who have temporal lobe epilepsy (TLE) due to other etiologies.   Methods : In this retrospective study all patients with a clinical diagnosis of TLE were recruited in a referral outpatient epilepsy clinic at Shiraz University of Medical Sc...

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P 111: Use of Stem Cell Therapy for Treatment of Temporal Lobe Epilepsy (TLE)

Epilepsy is one of the most common neuroinflammatory disorders that affect more than 50 million people worldwide. Excessive electrical discharges in neurons following neural cell damage or loss leads to recurrent seizures, which are described as epilepsy. One of the most common and difficult to treat types of epilepsy is Temporal Lobe Epilepsy (TLE), which results from hippocampal sclerosis. Cu...

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Endoscopic Transsphenoidal Resection of a Medial Temporal Arachnoid Cyst in a Patient with Temporal Lobe Epilepsy

Abstract Introduction: Arachnoid cysts are developmental cystic lesions which may be found as an incidental finding on neuroimaging or present with symptoms of headache, seizure and neurologic deficit. Presentation with seizure is more common with larger sizes and temporal location. Presentation with TLE is rare, and fenestration of cysts had variable results for seizure control. Here in, we r...

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ژورنال

عنوان ژورنال: Seizure

سال: 2015

ISSN: 1059-1311

DOI: 10.1016/j.seizure.2015.05.017